Our team spent countless hours researching and reviewing treatment for fleas to find the ten best options currently available on the market. We considered factors such as style, functionality, and value when making our selections. In this guide, you will find our top picks for the best treatment for fleas available.

Best treatment for fleas

Our Top 16 Best treatment for fleas Reviews

SaleRank No. 1
Vet's Best Flea and Tick Home Spray | Flea Treatment for Dogs and Home | Plant-Based Formula | 32...
  • TOTAL HOME & DOG DEFENSE: Applies easily on surfaces, indoors including dog bedding, crates, furniture, blankets, upholstery, carpets, and more. Also gentle enough to be applied directly on dogs and puppies 12 weeks or older.
  • GENTLE PROTECTION: Vet's Best Flea & Tick Home Spray uses plant-based ingredients to kill fleas, flea eggs, and ticks on contact.
  • PROVEN EFFECTIVE: Whether facing an active flea and tick problem or are applying for routine prevention, our spray is scientifically proven effective against pests but gentle enough to use around the whole family.
  • PLANT-BASED ALTERNATIVE - Battles fleas and ticks without harsh chemicals, but instead uses plant-based ingredients, such as peppermint oil and eugenol (from clove plants).
  • MADE IN THE USA: Our products are proudly manufactured in the USA with quality domestic and internationally sourced ingredients.
Rank No. 2
Advecta Ultra Flea And Tick Prevention For Dogs, Dog Flea And Tick Treatment, Waterproof Topical,...
  • BREAK THE FLEA LIFE CYCLE: Effectively breaks the flea life cycle by killing all life stages of fleas: adults, eggs and larvae
  • ACTIVE INGREDIENTS THAT WORK: Contains the same active ingredients as Bayer K9 Advantix II for Dogs (pyriproxyfen & imidacloprid)
  • FLEA TREATMENT FOR DOGS: Kills fleas and lice within 12 hours of drops application, and prevents reinfestations for up to 4 months
  • 5 WAY PROTECTION FOR DOGS: Advecta Ultra for Dogs provides 5 way protection against fleas, ticks, biting flies, mosquitoes and lice
  • WATERPROOF, FRAGRANCE-FREE FORMULA: Flea medication remains effective & provides protection even if your pet gets wet
Rank No. 3
FRONTLINE Plus for Dogs Flea and Tick Treatment (Extra Large Dog, 89-132 lbs.) 3 Doses (Red Box)
  • The name in flea & tick protection trusted by pet owners for over 20 years, this waterproof, fast-acting flea and tick treatment kills fleas, flea eggs, lice, and ticks, including those that may transmit Lyme disease.
  • Designed for use only with dogs and puppies, this long-lasting treatment is made for dogs eight weeks or older.
  • Made with two active ingredients, fipronil and (S)-methoprene, this treatment stops infestations and prevents new ones.
  • Applied on a single point on your pet, the treatment rapidly covers your dog's entire body and deposits in the sebaceous glands. These glands as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet.
  • One dose of FRONTLINE Plus lasts 30 days.
Rank No. 4
Hartz UltraGuard Topical Flea & Tick Prevention for Cats and Kittens - 3 Monthly Treatments
  • Topical drop formula kills fleas and deer ticks
  • Includes 3 monthly treatments in easy to apply, single dose tubes
  • Repels mosquitoes for 18 days
  • For use on cats and kittens 12 weeks and older weighing 5 pounds and over
SaleRank No. 5
Advantage II Flea Prevention and Treatment for Extra-Large Dogs (Over 55 Pounds), 4 Pack
  • 4-dose flea and lice treatment for extra-large dogs over 55 pounds
  • Advantage II dog flea treatment works through contact, so fleas don't have to bite your dog to die
  • Effective dog flea treatment kills fleas in multiple life stages (eggs, larvae and adults) to break the flea life cycle
  • Easy-to-apply flea and lice treatment for extra-large dogs starts working within 12 hours and protects for up to 30 days
  • Vet-recommended, fragrance-free and designed specifically to treat and prevent fleas and lice on dogs
Rank No. 6
Amazon Basics Flea and Tick Topical Treatment for Cats (over 1.5 pounds), 3 Count (Previously...
  • Same product, new look—This product is identical in manufacturing and formulation as the Solimo brand
  • Amazon Basics Flea & Tick starts eliminating fleas and ticks within 24 hours of treatment
  • Active ingredients prevent flea infestations by killing flea eggs, flea larvae, mosquitos, biting flies and chewing lice
  • One application provides up to 30 days of protection
  • Waterproof: 24 hours after application your pet's treatment is protected against rain and water activities
SaleRank No. 7
TevraPet Activate II Flea and Tick Prevention for Dogs | 4 Months Supply | Extra Large Dogs 55+ lbs...
  • COMPARE TO K9 ADVANTIX II II: Activate II uses Imidacloprid, Permethrin, and Pyriproxyfen - the same safe, fast acting active ingredients used in Advantix II for Dogs. Includes four (4) monthly doses
  • ACTIVELY PROTECTS YOUR DOG: Activate II is approved by veterinarians to repel and kill fleas and ticks on contact - before your dog is exposed to bites and potential flea borne illnesses
  • STOP INFESTATIONS FAST: Our topical drops prevent infestations by breaking the flea life cycle - our insect growth regulator (IGR) starts killing flea eggs and larvae within 12 hours of application
  • EASY TO APPLY: Simply apply to the base of your dog's neck, and the waterproof solution will travel across the skin - providing continuous protection for 30 days per application
  • MADE IN AMERICA - QUALITY GUARANTEED: TevraPet Activate II is made to the exacting standards we demand for our own pets. We're proud to help you protect your dog with confidence
Rank No. 8
FRONTLINE Plus for Dogs Flea and Tick Treatment (Small Dog, 5-22 lbs.) 8 Doses (Orange Box)
  • Trusted by vets for over 20 years, this waterproof, fast-acting flea and tick treatment kills fleas, flea eggs, lice, and ticks, including those that may transmit Lyme disease
  • Designed for use only with dogs and puppies, this long-lasting treatment is made for dogs eight weeks or older, weighing between 5 and 22 pounds
  • Made with two active ingredients, fipronil and (S)-methoprene, this treatment stops infestations and prevents new ones
  • Applied on a single point on your pet, the treatment rapidly covers your dog's entire body and deposits in the sebaceous glands. These glands as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet
  • One dose of FRONTLINE Plus lasts 30 days
Rank No. 9
Wondercide - Flea, Tick and Mosquito Spray for Dogs, Cats, and Home - Flea and Tick Killer, Control,...
  • KILLS & REPELS. Using natural essential oils, this spray is proven to kill by contact, repel, and prevent 98-100% of fleas, ticks and mosquitoes in laboratory testing. It breaks the flea life cycle by eliminating eggs, larvae, and adults.
  • TREAT NATURE WITH NATURE. When used as directed, a safe and effective alternative to collars, pills, chewables, and drops harnesses the power of nature. Holistic vet approved. Enjoy peace of mind knowing your pets and home are protected with our non-harsh formula.
  • SAFE FOR DOGS, CATS OF ALL AGES WHEN USED AS DIRECTED. Gentle enough to use on puppies, kittens, and senior pets when used as directed. Powerful enough to fully eliminate pests on the skin and fur. Safe to use around the entire family, and kid-safe, when used as directed. Mom owned, Mom approved.
  • 3-IN-1 PLANT-BASED SOLUTION. For dogs, cats, and home! A home remedy that kills fleas throughout the house on carpet, furniture, bedding, and flooring. Also a repellent in pet environments like dog kennels or cat condos. Calming Rosemary scent freshens homes.
  • POWERFULLY EFFECTIVE. Powered by nature and proven to work. Give your pet the advantage in protection against fleas and ticks with our non-harsh formula. Cruelty free and USA Made with U.S. and global components.
Rank No. 10
Adams Carpet Powder With Linalool and Nylar, Kills Fleas and Ticks On Contact, Kills All Stages of...
  • KILLS FLEAS - Kills fleas on contact for up to 30 days plus kills flea eggs and flea larvae for up to 1 year
  • LONG-LASTING CONTROL - Helps break the flea life cycle, controlling re-infestation for up to 365 days
  • KILLS TICKS - Kills ticks on contact
  • FRESH SCENT - Freshens and deodorizes your home with a pleasant citrus fragrance and eliminates deep-down pet odors
  • DUAL ACTION - Immediate and long-lasting effects* (*contains Linalool and pyrethrins to kill adult insects and Nylar to kill flea eggs/larvae for long-lasting control

The best way to find the right treatment for fleas for you is to do your research and read reviews. This article was created with the hope that you will be able to find the best treatment for fleas to suit your needs. We wish you the best of luck in your search and remember to share this article with your friends.

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